"Why Does High Hepatitis B Virus Load Occur?"

Factors Contributing to High Hepatitis B Virus Load and Clinical Management

A high hepatitis B virus (HBV) load can be attributed to various factors such as the acute phase of the illness, low immunity, lack of treatment, incorrect medication usage, and the presence of drug resistance. Clinical improvement can be achieved through general and pharmacological interventions. Here are the key points:

1. Acute Phase of the Illness

When a patient is in the acute phase of HBV infection, the virus is highly active and has a strong replication ability, leading to a continuous increase in viral load and enhanced infectivity. In this scenario, antiviral therapy is essential, with medications like Entecavir Dispersible Tablets and Interferon prescribed by a doctor to alleviate the condition.

2. Low Immunity

HBV infection triggers the immune system to produce specific antibodies against the virus. However, if the patient's immunity is low, it may fail to suppress the virus, resulting in an elevated viral load. General management measures include adjusting diet, improving sleep patterns, and avoiding prolonged periods of staying up late.

3. Lack of Treatment

Without treatment, HBV infection can progress, leading to a continuous increase in viral load. Patients should promptly seek medical attention and actively engage in treatment measures.

4. Incorrect Medication Usage

HBV patients are required to follow doctor's instructions for antiviral medication. Failure to do so can result in incomplete viral suppression, worsening the condition, and a sustained rise in viral load. In such cases, medication regimens need to be adjusted according to medical advice.

5. Drug Resistance

HBV mutations can lead to drug resistance, rendering conventional antiviral therapies ineffective. This allows the virus to continue replicating, increasing the viral load. Switching to more sensitive drugs like Acyclovir Tablets and Ganciclovir Capsules is necessary in such situations.

HBV patients should adhere to their doctor's recommendations, actively participate in treatment, engage in appropriate exercise, improve their physical fitness, and facilitate recovery.