Why Does Cirrhosis Cause Low Platelet Count?

Liver Cirrhosis and Reduced Platelet Counts

The reduction of platelet counts in patients with liver cirrhosis is primarily attributed to the decreased synthesis of coagulation factors by the liver. There are numerous factors that can lead to abnormal liver function clinically, such as viral hepatitis and alcoholic liver disease.

1. Causes:

Liver cirrhosis is a chronic progressive disease that often exhibits no obvious clinical symptoms or signs in its early stages. As the disease progresses, symptoms like abdominal pain, diarrhea, appetite loss, and weight reduction may gradually emerge. In severe cases, portal hypertension may develop, affecting the normal hematopoietic system. This can lead to excessive production of fibrous tissue in the body, causing splenomegaly (enlarged spleen) and inhibiting the formation of megakaryocytes in the bone marrow, ultimately resulting in a decrease in platelet counts.

2. Treatment:

For liver cirrhosis caused by underlying diseases, it is crucial to promptly seek further examination at a hospital to determine the underlying cause and then actively cooperate with medical professionals for targeted treatment. This may involve the use of antiviral medications like Entecavir Tablets or Tenofovir Alafenamide Fumarate Tablets for hepatitis B. Additionally, Compound Glycyrrhizin Capsules can be taken to protect the liver, and supplementary liver-protecting medications like Silybin Capsules or Bicyclol Tablets can be prescribed to promote liver cell repair and regeneration, alleviating symptoms. Furthermore, Interferon α-2b for Injection can be administered as prescribed to prevent infections, and surgical intervention may be necessary to remove the affected area, with commonly used procedures including Transjugular Intrahepatic Portosystemic Shunt (TIPS) and liver transplantation.

It is recommended to adopt healthy lifestyle habits in daily life, avoiding excessive fatigue and staying up late. A diet consisting of light, easily digestible foods, fresh fruits, and vegetables should be prioritized, while spicy, irritating, and greasy foods should be minimized to ensure balanced nutrition, beneficial for overall health.