Is an antibody titer of 1:2 serious, and can it still transmit infection?

Antibody Titer 1:2

Generally refers to the non-specific antibody, namely the anti-cardiolipin antibody titer, in syphilis patients. This titer level is typically not considered severe. However, even at a titer of 1:2, syphilis remains contagious, with higher titers indicating higher infectivity and activity. Syphilis is a contagious disease caused by the infection of Treponema pallidum. Upon infection, the human immune system produces various antibodies. A detected anti-cardiolipin antibody titer of 1:2 in syphilis is relatively low, suggesting limited infectivity. Nonetheless, it does not signify the absence of infectivity altogether. This titer may be observed in early stages of syphilis infection or after a prolonged infection where the antibody titer decreases, yet the presence of Treponema pallidum still indicates the potential for transmission. Hence, active treatment is necessary. It is recommended to follow a standardized treatment plan with medications like penicillin under medical supervision, including Benzathine Penicillin G, Procaine Penicillin G, and Aqueous Crystalline Penicillin G, until the titer turns negative, at which point the infectivity is generally considered absent.