How to Inject Progesterone? What Are Its Uses?

Progesterone, also known as progesterone hormone or corpus luteum hormone, is secreted by the ovaries in women. It plays a role in protecting the endometrium of the uterus and supporting early fetal growth and development during pregnancy. Under the influence of certain factors, some women may experience insufficient progesterone secretion, which requires progesterone injection for treatment. Many women are concerned about the injection method of progesterone. So, how to inject progesterone and what are its benefits? Let's take a look below.

I. How to Inject Progesterone?

The most common method of using progesterone injection is intramuscular injection. The progesterone injection is directly drawn into a syringe and injected into the gluteal muscle of the patient, with alternating injection on both sides of the buttocks. Since progesterone injection is an oily solution with a high drug concentration, there may be resistance during the injection process, resulting in a feeling of pain and swelling at the injection site, which is normal. Additionally, the injection site may be prone to hardness or pain, which may take several days to recover. When injecting progesterone, it is important to inject slowly and evenly to minimize patient discomfort. Avoid repeated injection in the same area to reduce the risk of local hardness.

Once the condition stabilizes, the injection can be switched to oral administration. Oral progesterone formulations include progesterone soft capsules and dydrogesterone tablets.

II. What are the Benefits of Progesterone?

1. Promotes the development of the fertilized egg by reducing the excitability of the pregnant uterus and inhibiting its activity, allowing the fetus to grow safely.
2. Controls the timing of menstruation. Progesterone can effectively control the specific time of menstruation. The medication is typically taken for 3-5 days, and menstruation occurs 3 days after stopping the medication.
3. Supports lactation. Together with estrogen, progesterone promotes the full development of the breasts, preparing them for lactation.
4. Provides a clinical diagnostic basis. Progesterone is clinically used for reactive diagnosis of amenorrhea or the causes of amenorrhea, such as threatened abortion and habitual abortion.
5. Affects the endometrium. It thickens the endometrium and allows it to grow firmly on the uterine wall, preparing it for the implantation of the fertilized egg and delaying menstruation.
6. Protects fetal memory. Progesterone can reduce the sensitivity of the uterus to oxytocin and estrogen, so an appropriate amount of progesterone supplementation can have a beneficial effect on protecting fetal memory.
7. Suppresses ovulation. It closes the cervix, reduces and thickens mucus, making it difficult for sperm to penetrate. In large doses, it inhibits the secretion of pituitary gonadotropins through negative feedback on the hypothalamus, suppressing ovulation.
8. Has sedative and menstrual regulation effects, harmonizing the reproductive system and preventing threatened and habitual abortions.