What Causes Frequent Gout Attacks?

Gout attacks frequently may be related to non-disease factors such as improper diet and medication, as well as disease factors including infection, obesity, kidney disease, and endocrine disorders.

Non-Disease Factors

1. Improper diet: If one does not pay attention to a balanced diet in daily life and consumes excessive amounts of high-purine foods, such as animal organs and seafood, it may lead to elevated uric acid levels in the body, thus triggering gout attacks.

2. Medication: After taking diuretics such as furosemide and pyrazinamide, some patients may experience a decrease in blood uric acid levels. However, if they subsequently consume a large amount of high-purine foods, it can easily lead to recurrent gout attacks.

Disease Factors

1. Infection: When the body is infected with bacteria or viruses, it releases a large amount of toxins and inflammatory mediators, affecting metabolic balance in the body and increasing the risk of gout.

2. Obesity: People with overweight or obesity often experience abnormal purine metabolism in the body, leading to gout attacks.

3. Kidney disease: Conditions such as renal insufficiency or chronic kidney failure affect uric acid excretion, causing uric acid salts to deposit around joints and form crystals, resulting in frequent gout attacks.

4. Endocrine disorders: Long-term staying up late, excessive mental stress, or being in menopause can all lead to endocrine imbalance, increasing uric acid production and subsequently causing gout attacks.

In addition to the above situations, underlying diseases such as diabetes, hypertension, and coronary atherosclerotic heart disease can also affect normal blood circulation and even exacerbate conditions. Therefore, it is recommended to seek medical attention promptly.