How long after receiving the pentavalent vaccine will adverse reactions appear?

Receiving the five-in-one vaccine typically refers to the administration of the combined vaccine. Generally, adverse reactions may occur approximately 5 to 24 hours after receiving the five-in-one vaccine. The five-in-one vaccine can replace vaccines such as the polio vaccine and the diphtheria, tetanus, and pertussis (DTP) vaccine. After vaccination, it stimulates the body to produce corresponding antibodies, thereby preventing diseases such as diphtheria, pertussis, tetanus, meningitis, pericarditis, and bacteremia caused by Haemophilus influenzae type B. The five-in-one vaccine elicits an immune response in the body. For some individuals, it may produce pyrogenic factors in the body, leading to adverse reactions such as fever and vomiting. If an individual has a thinner skin stratum corneum, pain at the injection site may also occur after vaccination. Such adverse reactions usually appear about 5 to 24 hours after vaccination and are normal reactions. Generally, no special treatment is required, and enhancing daily life and dietary care is sufficient. After receiving the five-in-one vaccine, keep the injection site clean to avoid infection. Avoid consuming strong tea, coffee, and alcoholic beverages after vaccination to prevent interference with the vaccine's effectiveness.