"What Does Multiple Gastric Ulcers Mean?"

Multiple Gastric Ulcers

Multiple gastric ulcers refer to multiple circular or elliptical defects of varying sizes appearing on the gastric mucosa, with neat edges and smooth bottoms. Multiple gastric ulcers are a type of peptic ulcer.

Causes

1. Helicobacter pylori infection: If a patient is infected with Helicobacter pylori, it may lead to excessive gastric acid secretion, thereby causing gastric injury and ultimately inducing the disease.
2. Medication factors: Long-term use of non-steroidal anti-inflammatory drugs (NSAIDs) also increases the risk of developing gastric ulcers, such as aspirin enteric-coated tablets and indomethacin capsules. These drugs inhibit prostaglandin synthesis, affecting the defensive role of gastric mucosal cells against damaging factors, leading to gastric ulcers.
3. Stress state: When the body is under stress conditions such as severe trauma, major surgery, or other critical illnesses, the sympathetic nerves become excited, and the adrenal medulla releases catecholamines, which directly stimulate gastric parietal cells to secrete gastric acid. The function of the gastric mucus-bicarbonate barrier is impaired, further exacerbating the injury to the gastroduodenal mucosa, ultimately leading to the formation of gastric ulcers.

Treatment

For patients with multiple gastric ulcers without complications, acid suppressants such as omeprazole sodium enteric-coated tablets and pantoprazole sodium enteric-coated tablets can be used under medical supervision. If combined with Helicobacter pylori infection, antibiotics such as amoxicillin capsules and clarithromycin capsules should be administered concurrently as prescribed.

When necessary, endoscopic hemostasis or other procedures can be considered.