What Are the Effects of Drospirenone and Ethinyl Estradiol Tablets?

Drospirenone and ethinyl estradiol tablets are used to regulate menstrual cycles and serve as contraceptives. In some cases, they may be prescribed for patients after surgical abortions to reduce bleeding and contract the uterus. Additionally, this medication can also be used to treat mild acne in women. It is important to note that drospirenone and ethinyl estradiol tablets are prescription drugs and should only be used as prescribed by a doctor.

When taken correctly, drospirenone and ethinyl estradiol tablets can affect the normal development of eggs and prevent the formation of fertilized eggs, thus serving as a contraceptive. They can also be used to treat menstrual irregularities, reduce bleeding by constricting endometrial blood vessels after surgical abortions, and treat mild acne in women.

Drospirenone and ethinyl estradiol tablets are contraindicated in patients with severe cardiovascular diseases, thrombotic diseases such as hypertension, coronary heart disease, and venous thrombosis. They are also contraindicated in patients with chronic hepatitis or nephritis, some malignancies, precancerous lesions, and endocrine diseases such as diabetes and hyperthyroidism. Additionally, they should not be used during lactation. Smoking women over 35 years of age may have an increased risk of cardiovascular diseases after taking these tablets, and therefore, long-term use is not recommended.

The three most common treatment-related adverse events associated with drospirenone and ethinyl estradiol tablets (with an incidence rate of over or close to 5%) are irregular uterine bleeding (6.3%, 36 cases), nausea (4.7%, 27 cases), and mood swings (5.6%, 32 cases). These adverse effects are known reactions to combined oral contraceptives.