What Are the Effects and Side Effects of Oral Administration of Gentamicin?

Oral administration of gentamicin has excellent effects and curative effects on digestive system diseases, urinary tract infections, traumatic inflammation, and skin injuries. However, it has a significant impact on the vestibular system, mainly manifesting as dizziness, vertigo, and tinnitus.

1.1 It has excellent effects and curative effects on digestive system diseases, such as acute gastroenteritis, acute enteritis, ulcerative colitis, or conditions such as cholecystitis, pancreatitis, and bile reflux gastritis. Oral administration of gentamicin can be used in these cases.

1.2 It can treat some urinary tract infections. For example, in acute cystitis and acute pyelonephritis, intravenous injection of gentamicin may have certain nephrotoxicity, so oral administration of gentamicin can be used for treatment.

1.3 Traumatic inflammation and skin injuries can also be treated with oral administration of gentamicin combined with topical application of gentamicin, which can achieve good anti-inflammatory effects.

2.1 Similar to kanamycin, it has a significant impact on the vestibular system and less damage to the cochlea, mainly manifesting as dizziness, vertigo, and tinnitus. Special attention should be paid to toxic reactions in patients with renal insufficiency or children, as severe cases may lead to hearing loss or even deafness.

2.2 Since this drug has a blocking effect on neuromuscular junctions, it is not suitable for intravenous injection or rapid intravenous infusion in large doses to prevent respiratory depression.