"Can Excessive Intravenous Fluids Lead to Uremia?"

Excessive intravenous infusion generally does not lead to uremia. Uremia is the common outcome of various kidney diseases progressing to the later stage. Common causes include chronic glomerulonephritis, diabetic nephropathy, hypertensive nephropathy, and inherited nephropathy. Simply having too much intravenous infusion does not cause these diseases, so excessive intravenous infusion does not cause uremia.

1. Chronic Glomerulonephritis

By affecting the glomerular filtration function, it can cause the body to exhibit symptoms such as proteinuria, hematuria, edema, and hypertension. By controlling blood pressure and reducing proteinuria, the deterioration of renal function can be delayed. If well-controlled, it generally does not progress to uremia.

2. Diabetic Nephropathy

Early diabetic nephropathy may have no obvious symptoms. As the disease progresses, symptoms such as proteinuria and edema may appear. If well-controlled at this stage, it will not progress to uremia. However, if diabetic nephropathy progresses rapidly, uremic symptoms such as fatigue and dizziness may gradually appear.

3. Hypertensive Nephropathy

Long-term hypertension can damage the small arteries of the kidney, leading to their sclerosis and decreased renal function. Early stages may have no obvious symptoms, while some patients may experience fatigue, increased nocturia, and low back pain. When the disease is well-controlled, it generally does not progress to uremia.

4. Inherited Nephropathy

Conditions such as polycystic kidney disease and hereditary nephritis may present with increased urine output and edema, but typically do not progress to uremia. Additionally, if patients have underlying conditions such as chronic heart failure, which can increase the burden on the heart, excessive intravenous infusion may further exacerbate this burden and hinder disease control. Therefore, it is recommended that patients actively control their blood pressure, seek treatment under medical supervision, and avoid self-medication or increasing dosages.