What Are the Four Coagulation Tests Done During Pregnancy?

Pregnancy usually refers to gestation, while coagulation four items often refer to coagulation four-item test, which mainly involves prothrombin time, activated partial thromboplastin time, thrombin time, and fibrinogen. These tests can determine whether coagulation function is normal.

Prothrombin time is mainly used to judge whether extrinsic coagulation is normal. The normal range is generally 11-13 seconds. If it exceeds the normal value by 3 seconds, it indicates an abnormality.

Activated partial thromboplastin time is mainly used to check endogenous coagulation function. The normal range is generally 25-35 seconds. If it exceeds the normal value by 10 seconds, it indicates an abnormality in endogenous coagulation function.

Thrombin time is mainly used to reflect the fibrinogen in the plasma. By observing the time of plasma coagulation, it can judge whether the coagulation function, anticoagulant function, and fibrinolytic system are normal. The normal range is generally 16-18 seconds. If it exceeds the normal value by 3 seconds, it will be diagnosed as abnormal.

Fibrinogen is the highest concentration of coagulation factor in the plasma. Under the action of thrombin, it may be transformed into fibrin, which can assist in the diagnosis of hemorrhagic diseases and thrombotic diseases. If the test results are abnormal, it is necessary to seek medical attention promptly to avoid delaying the best treatment opportunity.