What are the early symptoms of primary sclerosing cholangitis?

Update Date: Source: Network

Early Symptoms of Primary Sclerosing Cholangitis

The early symptoms of primary sclerosing cholangitis (PSC) primarily encompass skin itching, fatigue in extremities, jaundice, loss of appetite, and abdominal distension. It is recommended that patients promptly seek medical attention to prevent disease progression. Detailed analyses are as follows:

1. Skin Itching

PSC is often attributed to poor dietary habits, which can disrupt bile secretion, subsequently irritating skin mucous membranes and causing itching.

2. Fatigue in Extremities

If PSC is caused by bacterial infection in the bile ducts, it may compromise the immune system, leading to symptoms such as mental lethargy and fatigue.

3. Jaundice

Without effective treatment, bilirubin levels in the body may elevate, triggering jaundice, characterized by changes in skin color.

4. Loss of Appetite

As the disease progresses, pressure within the biliary tract may increase, potentially impeding bile excretion, which can adversely affect appetite.

5. Abdominal Distension

In severe cases, intra-abdominal pressure may rise, resulting in abdominal bloating and discomfort.

Other potential symptoms include splenomegaly (enlarged spleen) and dull pain in the right upper quadrant of the abdomen.

Patients with PSC can be treated with medications such as Xiaoyan Lidan Pian (anti-inflammatory and gallbladder-stimulating tablets), Xiaoxuan Shanlangdang Alkaloid Tablets, and Ursodeoxycholic Acid Capsules under the guidance of a physician.