What are the early symptoms of primary sclerosing cholangitis?
Early Symptoms of Primary Sclerosing Cholangitis
The early symptoms of primary sclerosing cholangitis (PSC) primarily encompass skin itching, fatigue in extremities, jaundice, loss of appetite, and abdominal distension. It is recommended that patients promptly seek medical attention to prevent disease progression. Detailed analyses are as follows:
1. Skin Itching
PSC is often attributed to poor dietary habits, which can disrupt bile secretion, subsequently irritating skin mucous membranes and causing itching.
2. Fatigue in Extremities
If PSC is caused by bacterial infection in the bile ducts, it may compromise the immune system, leading to symptoms such as mental lethargy and fatigue.
3. Jaundice
Without effective treatment, bilirubin levels in the body may elevate, triggering jaundice, characterized by changes in skin color.
4. Loss of Appetite
As the disease progresses, pressure within the biliary tract may increase, potentially impeding bile excretion, which can adversely affect appetite.
5. Abdominal Distension
In severe cases, intra-abdominal pressure may rise, resulting in abdominal bloating and discomfort.
Other potential symptoms include splenomegaly (enlarged spleen) and dull pain in the right upper quadrant of the abdomen.
Patients with PSC can be treated with medications such as Xiaoyan Lidan Pian (anti-inflammatory and gallbladder-stimulating tablets), Xiaoxuan Shanlangdang Alkaloid Tablets, and Ursodeoxycholic Acid Capsules under the guidance of a physician.