What Causes High Creatinine Levels with Normal Urinalysis Results?

Normal urine routine with high creatinine levels can be caused by physiological factors, urinary obstruction, chronic glomerulonephritis, etc. 1. Physiological factors: It is most common in some meat-eaters, as a long-term meat-based diet can lead to a significant increase in creatinine levels. It may also occur after intense exercise, as exercise itself increases muscle metabolism, leading to excessive creatinine production. 2. Urinary obstruction: Mostly caused by urinary system diseases such as ureteral calculi and urethral calculi, which can lead to urine retention, increased renal capsular pressure, and significantly reduced glomerular filtration rate, resulting in decreased creatinine excretion. 3. Chronic glomerulonephritis: It can cause glomerular necrosis and significantly reduced filtration rate, affecting creatinine excretion and leading to increased creatinine levels. Besides the above reasons, it may also be caused by other diseases, such as acute tubular necrosis. If physiological factors are ruled out, it is necessary to seek medical attention promptly and cooperate with doctors to identify the cause for targeted treatment.