Is it advisable to keep a child with sexual chromosome abnormalities?

Pregnant mothers with sex chromosome abnormalities detected through non-invasive screening are recommended to undergo amniocentesis. This is because it is necessary to distinguish which karyotype is involved, with the female karyotype being 46XX and the male being 46XY. If a female fetus has an extra X chromosome, it is called super-female syndrome, or 47XX. Actually, such fetuses can be kept because many clinically similar cases have been encountered, and follow-up has found the children to be normal.

Another scenario is when sex chromosome abnormalities are detected during non-invasive screening, but no abnormalities are found upon further testing, and the mother is found to have three X chromosomes. Therefore, such children are recommended to be born. If a fetus lacks an X chromosome, it is called Turner syndrome. Such children may exhibit absence of menstruation, small uterine development, and short stature. Although they may not have intellectual disabilities, they may not appear as intelligent, which is unacceptable to most mothers.

For males, having an extra Y chromosome may result in violent tendencies or a bad temper. However, this does not affect fertility or intelligence. Another condition is when a male has an extra X chromosome, resulting in 47XXY, which is known as Klinefelter syndrome. The main manifestation is azoospermia and infertility, although it may not be visually apparent. Some pregnant women are willing to carry such fetuses to term. However, when sex chromosome abnormalities are detected, amniocentesis must be performed.