Does prolonged use of antibiotics lead to anemia?
Long-term Antibiotic Use and Its Potential Risks
Prolonged use of antibiotics may lead to anemia, particularly with medications such as metformin tablets, aspirin enteric-coated tablets, and erythromycin enteric-coated tablets, which may inhibit folate metabolism in the body, resulting in anemia. Regular antibiotic drugs, however, generally do not cause anemia.
Long-term antibiotic consumption can also disrupt gut flora balance, impair renal and hepatic functions, among other effects, all of which can contribute to anemia.
1. Folate Metabolism:
Chronic antibiotic use can hinder folate metabolism, leading to folate deficiency and, consequently, anemia. Thus, antibiotic use should be supervised by a medical professional to avoid self-medication or dosage increments.2. Gut Flora Imbalance:
Patients on long-term antibiotics may experience gut flora disturbances, manifesting as appetite loss, diarrhea, and digestive issues. Furthermore, it predisposes individuals to fungal infections, which can also lead to anemia.3. Renal Dysfunction:
Long-term administration of antibiotics like erythromycin enteric-coated tablets and azithromycin capsules can damage the kidneys, leading to renal dysfunction marked by proteinuria and hematuria.4. Hepatic Dysfunction:
Some antibiotics possess hepatotoxicity and can cause liver damage over time, resulting in conditions like hepatitis and cirrhosis. Additionally, they may induce bile stasis, which can lead to gallstones, cholangitis, and anemia.Prolonged antibiotic use can also foster drug resistance, predisposing individuals to secondary infections, detrimental to overall health. Hence, when ill, it's crucial to adhere to physician-prescribed medication regimens and avoid extending treatment durations without consultation.
During treatment, a balanced, nutritious diet is advised, steering clear of spicy and irritant foods.
