Where is the appendix located?

Anatomy and Function of the Appendix

The appendix, primarily located in the lower right quadrant of the abdomen, attaches to the posteromedial wall of the cecum. Its proximal end opens into the cecum, approximately at the intersection of the outer one-third of the line connecting the navel to the anterior superior iliac spine on the right side. This location is clinically known as McBurney's point.

Regarding the function of the appendix, it was once believed to be a vestigial organ with no definitive physiological role. However, recent research indicates that the appendix may possess certain immunological functions. The appendix is rich in lymphoid tissue, which could play a crucial role in local immune responses. Notably, when the intestines are invaded by harmful microorganisms, the appendix may assist the body in fighting infections by producing antibodies.

Furthermore, the appendix is involved in the maturation process of B lymphocytes, which is vital for the immune function of the body. Nevertheless, due to the appendix's unique anatomical structure and location, its lumen is narrow, and its opening is prone to obstruction, thereby increasing the risk of appendicitis. Appendicitis is a common abdominal emergency that, if left untreated, can lead to severe complications or even be life-threatening.