What Type of Blocker is Atropine?

Atropine belongs to the category of M-receptor antagonists. Its primary function is to inhibit the inhibitory effect of the vagus nerve on the heart, relieving small vessel spasms and smoothing muscle spasms. It is often used in the treatment of organophosphorus poisoning, relief of angina pectoris, ophthalmological dilation of pupils, and other applications. When using this medication, it is essential to follow medical advice and be aware of its potential adverse reactions.

Atropine is an M-receptor antagonist, extracted from solanaceous plants as racemic atropine. It is also known as atropine sulfate. Its main functions include inhibiting the inhibitory effect of the vagus nerve on the heart, relieving smooth muscle spasms, relieving small vessel spasms, and suppressing glandular secretions.

Atropine is commonly used in the following scenarios:

1. Organophosphorus poisoning: In cases of organophosphorus poisoning, large doses of atropine can dilate the pupils and aid in the treatment of the poisoning.
2. Relief of visceral cramps: Such as gastrointestinal spasms and cramps, renal colic, and biliary colic.
3. Sinus bradycardia or atrioventricular block: Atropine can increase heart rate.
4. Ophthalmology: Due to its pupil dilation effects.

Common adverse reactions to atropine include:

1. Constipation, reduced sweating (which can lead to hyperthermia due to blocked sweat excretion), dryness of the mouth, nose, throat, blurred vision, skin flushing, difficulty urinating (especially in elderly patients who may be at risk of acute urinary retention), reduced gastrointestinal motility, and gastroesophageal reflux.
2. Less commonly, atropine may cause elevated intraocular pressure, allergic skin rashes or blisters.
3. Long-term topical application of atropine to the eyes can cause local allergic reactions (drug-induced blepharoconjunctivitis).

When using atropine, it is important to follow medical advice closely and be aware of its potential side effects.