How to Treat Myeloproliferative Neoplasms?

Myeloproliferative neoplasms are common diseases in the oncology department, often occurring in middle-aged men around 50 years old and chronic infectors. After the onset of this disease, patients usually experience symptoms such as pain, osteoporosis, anemia, and hypercalcemia. If not treated promptly, it can easily induce severe complications such as peripheral neuropathy. After the occurrence of myeloproliferative neoplasms, chemotherapy and radiotherapy are usually the main treatments. If there is spinal cord compression, surgical treatment can be performed. The specific treatment methods for this disease are as follows:

1. Chemotherapy: The primary treatment for myeloproliferative neoplasms is chemotherapy. The most commonly used chemotherapy drugs are melphalan, vincristine, and doxorubicin. Adrenal cortical hormones, androgens, and interferons can also be used for patients with severe symptoms.

2. Radiotherapy: Patients with myeloproliferative neoplasms usually undergo local radiotherapy. The main role of local radiotherapy is to relieve local pain, reduce tumor burden, control the progression of the lesion, and indirectly relieve spinal cord compression. This method has a very obvious effect on the control of local tumors.

3. Surgical Treatment: Surgery is also a commonly used method for treating this disease. The most commonly used surgical method is wide excision. This surgical method is usually suitable for patients with isolated myeloproliferative neoplasms without systemic symptoms or other lesions. During surgery, the tumor should be widely excised. If the tumor boundary is sufficiently clear, radiotherapy and chemotherapy are not required.