Who Are the Ideal Candidates for Injection Piperacillin?
The indication of Piperacillin Sodium for Injection is suitable for septicemia, upper urinary tract and complex urinary tract infection, respiratory infection, biliary tract infection, abdominal infection, pelvic infection, and skin and soft tissue infection caused by sensitive Enterobacteriaceae, Pseudomonas aeruginosa, and Acinetobacter species. Piperacillin can also be used in combination with aminoglycosides for the treatment of infections in patients with granulocytopenia and immune deficiency. Respiratory infection and biliary tract infection are relatively common, and these manifestations can be improved with Piperacillin Sodium for Injection. This product can also alleviate abdominal infection and improve pelvic infection, skin and soft tissue infection, etc. Use of this product may result in allergic reactions, local adverse reactions, and gastrointestinal adverse symptoms. Adverse reactions include: 1. Allergic reactions: Allergic reactions to penicillin drugs are common, including various types of rash such as urticaria, leukopenia, interstitial nephritis, asthma attacks, and serum sickness-like reactions. Severe reactions such as anaphylactic shock are occasionally seen. Once anaphylactic shock occurs, immediate resuscitation should be performed, including maintaining airway patency, oxygen administration, and administration of epinephrine, glucocorticoids, and other treatment measures. 2. Local symptoms: pain at the injection site, thrombophlebitis, etc. 3. Gastrointestinal symptoms: diarrhea, loose stools, nausea, vomiting, etc.; pseudomembranous colitis is rare. 4. Some patients may experience biliary cholestatic jaundice. 5. Central nervous system symptoms: headache, dizziness, and fatigue, etc. 6. When used in patients with renal insufficiency in large doses, due to the increase of cerebrospinal fluid concentration, penicillin encephalopathy may occur. Therefore, dose adjustment should be made according to renal function at this time.