"Why Does the 23-Valent Pneumococcal Vaccine Often Cause Fever?"

Explanation of Fever After 23-Valent Pneumococcal Vaccine Administration

The 23-valent pneumococcal vaccine is an inactivated vaccine, containing no live bacteria components, and generally does not cause infection. The primary reasons for fever after vaccination are allergic reactions and other factors, detailed as follows:

1. Allergic Reactions:

The 23-valent pneumococcal vaccine comprises certain antigenic components of Streptococcus pneumoniae, which stimulate the body's immune response, generating protective antibodies to prevent pneumonia caused by this bacterium. However, these antigens may trigger excessive immune reactions, leading to allergic responses, including fever and associated symptoms such as rash. In rare cases, severe reactions like chest tightness, difficulty breathing, or shock may occur, necessitating prompt medical attention.

2. Other Causes:

Fever induced by the 23-valent pneumococcal vaccine is typically transient and resolves quickly. If fever persists or manifests as high fever, immediate medical attention is advised. Differential diagnosis with fever stemming from other causes, such as influenza or pulmonary tuberculosis, is crucial.

Post-Vaccination Fever Management:

Fever after vaccination is most commonly attributed to allergic reactions and can often be alleviated through rest and adequate hydration. In cases of severe symptoms, medication under medical supervision is recommended.