"Does Taking Medication for Depression Cause Weight Gain?"
Effects of Antidepressants on Weight Gain
Whether taking antidepressants leads to weight gain depends on specific circumstances. If 5-hydroxytryptamine reuptake inhibitors (SSRIs) are chosen, they generally do not cause weight gain. However, if tricyclic antidepressants (TCAs), tetracyclic antidepressants, or other types of antidepressants are taken, they may lead to weight gain.
1. SSRIs (5-Hydroxytryptamine Reuptake Inhibitors)
Representative drugs include Sertraline Hydrochloride Tablets and Fluvoxamine Maleate Capsules. This class of drugs is currently one of the most frequently used antidepressants in clinical practice. They work by blocking 5-hydroxytryptamine receptors in the central nervous system. During treatment, they typically do not adversely affect the patient's body and do not cause obesity.
2. Tricyclic Antidepressants (TCAs)
Examples include Chlorpromazine Hydrochloride Tablets and Amitriptyline Hydrochloride Tablets. These drugs belong to the traditional category of antidepressants and are now used less frequently due to their numerous side effects. Long-term use can lead to cumulative toxicity and subsequent weight gain, accompanied by symptoms such as drowsiness and constipation.
3. Tetracyclic Antidepressants
Drugs like Duloxetine Hydrochloride Enteric-coated Tablets and Paroxetine Hydrochloride Tablets fall into this category, which is also commonly used for depression treatment. However, they can also cause weight gain to a certain extent due to their sedative effects. During medication, it is important to observe any changes in the body.
Apart from these common drugs, there are also newer antidepressants like Escitalopram Oxalate Tablets and Citalopram Hydrobromide Tablets. While these drugs are effective, they may also cause weight gain. It is recommended to follow medical advice and take medications as prescribed, avoiding self-medication, discontinuation, or dosage adjustments without guidance, as this may impact recovery.
