"What are the Symptoms and Treatments for Dermatomyositis?"

Symptoms and Treatment of Panniculitis

1. Panniculitis is an inflammation originating in the adipose tissue. Its primary and typical symptom is the recurrent occurrence of subcutaneous nodules in batches. These nodules are usually 1 to 2 centimeters in size, with larger ones exceeding ten centimeters. They are mildly elevated, with normal skin color, limited mobility, and significant pain or tenderness upon touch. They commonly occur on the buttocks and lower limbs.

2. During acute episodes, patients may also experience systemic symptoms such as fever, fatigue, muscle, and joint pain. Additionally, panniculitis can cause visceral damage, involving various organs and tissues. Extensive involvement often leads to a poor prognosis.

3. In terms of treatment, fibrinolytic agents or antimalarials like hydroxychloroquine can be administered. Furthermore, a combination of immunosuppressants such as azathioprine, cyclophosphamide, and thalidomide can also be effective.

4. During acute inflammatory phases or high fever, glucocorticoid therapy or a combination of non-steroidal anti-inflammatory drugs (NSAIDs) is necessary. With effective treatment, most patients' conditions can be controlled.