What are the Effects of Sodium Ferulate for Injection?

Many people are not particularly familiar with sodium ferulate, which is an injectable drug mainly used to dilate blood vessels and restore their elasticity. For atherosclerosis and cardiovascular and cerebrovascular diseases, this drug can be used under the guidance of a doctor. Since it is an injectable drug, it cannot be used without a doctor's prescription and must be administered in a hospital. Let's briefly understand the relevant content.

1. Effects of Sodium Ferulate Injection

Sodium ferulate injection has the effects of dilating blood vessels, reducing blood lipids, and improving small artery spasms. Atherosclerosis is generally related to excessive consumption of greasy food. By reducing blood lipids, this drug can gradually restore vascular elasticity, increase myocardial blood flow, and improve symptoms of myocardial ischemia. It is mainly used to treat symptoms such as chest tightness, shortness of breath, precordial pain, dizziness, and headache caused by ischemic cardiovascular and cerebrovascular diseases. Proper combinations can achieve better results in the treatment of cardiovascular and cerebrovascular diseases. For example, chest tightness and shortness of breath can be treated with compound Danshen tablets, and precordial pain can be treated with Danshen dripping pills, simvastatin, and metoprolol.

The side effects of this drug are relatively few. Some people may experience skin itching during use, which will gradually disappear after discontinuation. Unless they have allergies, they can use this drug with confidence.

2. Dosage and Administration

Intravenous drip: 0.1-0.3g once a day, dissolved in 100-500mL of glucose injection, normal saline, or glucose and sodium chloride injection for intravenous administration. Intramuscular injection: 0.1g once a day, 1-2 times a day, dissolved in 2-4mL of normal saline before use. The recommended course of treatment is 10 days.

3. Pharmacological Effects

Animal studies have shown that sodium ferulate can inhibit the production of malondialdehyde and thromboxane B2, reduce myocardial edema and the release of lactate dehydrogenase, and promote the production of 6-keto-prostaglandin F1α. It has antiplatelet aggregation, vasodilatory, and myocardial protective effects.