What Medications Can Help Lower High Uric Acid Levels?

Dietary management can reduce blood uric acid levels by 80 to 100 mmol/L. If, based on this, blood uric acid levels have not yet reached the normal range, medication should be prescribed. Firstly, based on the patient's urine routine results, it is recommended whether or not to take sodium bicarbonate tablets. On this basis, there are two aspects to consider when choosing medication for patients: one is to suppress uric acid production and the other is to promote uric acid excretion. It is necessary to make appropriate choices based on the different causes of increased uric acid levels in patients, and comprehensive management is the scientific approach to managing blood uric acid levels.

High uric acid is a metabolic disease caused by a disruption in the metabolism of a substance called purine in the body, leading to an increase in uric acid in the blood. The daily production and excretion of uric acid in the body are approximately equal. One-third of the production comes from food, while two-thirds is synthesized internally. One-third is excreted through the intestine, and two-thirds is excreted through the kidneys. A reasonable diet and controlling weight are important factors in preventing hyperuricemia and gout, as overweight or obesity are associated with an increased risk of hyperuricemia.

1. Low-fat diet: Most patients with hyperuricemia also have hyperlipidemia, and a high-fat diet can lead to increased utilization of exogenous fats. Therefore, a low-fat diet should be adopted.

2. Protein: A high-protein diet can lead to increased endogenous purine synthesis, which may increase the precursors of uric acid. Therefore, protein intake should be limited.