"Is High Aspartate Aminotransferase (AST) Level a Concern?"
In clinical settings, elevated AST levels may be caused by liver diseases, heart diseases, muscle injuries, alcoholism, and drug side effects, among others. For patients with elevated AST, it is crucial to seek medical attention promptly, undergo detailed examinations to determine the underlying cause, and adopt corresponding treatment measures under the guidance of a physician. The specifics are as follows:
1. Liver Diseases
The most common reason for elevated AST is liver diseases, such as hepatitis, fatty liver, and liver cirrhosis. Damaged liver cells release AST into the bloodstream. If AST levels persistently rise, it is recommended to promptly seek medical attention and undergo a comprehensive liver function examination. Based on the examination results, physicians may prescribe medications like liver protective tablets or compound glycyrrhizin tablets. Patients must strictly follow the physician's instructions for medication use.
2. Heart Diseases
Heart diseases like myocardial infarction and myocarditis can also lead to elevated AST. Patients with heart diseases should regularly undergo electrocardiogram (ECG) and echocardiography examinations. When necessary, medications like isosorbide mononitrate tablets or compound Danshen tablets may be prescribed under physician guidance. Patients must strictly follow the physician's instructions for medication use.
3. Muscle Injuries
Severe muscle injuries or muscle diseases like muscular dystrophy can also cause elevated AST. Patients with muscle injuries should engage in appropriate rest and rehabilitation training to avoid overexertion. If necessary, medications like compound glucosamine tablets or non-steroidal anti-inflammatory drugs may be prescribed under physician guidance. Patients must strictly follow the physician's instructions for medication use.
4. Alcoholism
Long-term heavy drinking can lead to alcoholic hepatitis, which in turn causes elevated AST. Abstinence is the primary measure in treating alcoholic hepatitis. After abstinence, liver function may gradually return to normal. Physicians may recommend medications like compound glycyrrhizin injection for treatment. Patients must strictly follow the physician's instructions for medication use.
5. Drug Side Effects
Certain medications, such as statins for lipid-lowering and antibiotics, may cause abnormal liver function, leading to elevated AST. If drug-induced AST elevation is suspected, patients should immediately discontinue the medication and seek medical attention. Physicians may adjust the medication regimen or prescribe liver-protecting medications like silybin capsules for treatment. Patients must strictly follow the physician's instructions for medication use.
To prevent and control health issues related to elevated AST, it is recommended to maintain a healthy lifestyle and dietary habits, avoiding overexertion and long-term alcohol consumption. For individuals experiencing related symptoms, it is crucial to promptly seek medical attention and inform physicians of possible underlying causes to receive timely treatment and intervention.