"What Causes Joint Pain in Osteoarthritis?"

Osteoarthritis: A Comprehensive Overview

Osteoarthritis (OA) is a joint disorder primarily characterized by the deterioration of articular cartilage, which subsequently affects the entire joint structure. This condition often leads to joint pain, primarily associated with inflammatory responses, joint degeneration, synovial proliferation, and bone hyperplasia.

1. Inflammatory Responses

In OA, inflammatory factors stimulate surrounding tissues, eliciting localized symptoms such as redness, swelling, heat, and pain, ultimately contributing to joint pain.

2. Joint Degeneration

As individuals age, organ functions, including those of bones and muscles, gradually decline. Osteoporosis may develop, predisposing individuals to OA, especially when engaging in prolonged weight-bearing activities or excessive physical exertion. Under the influence of inflammatory factors, joint pain characteristic of OA can manifest.

3. Synovial Proliferation

OA prompts inflammatory factors to stimulate synovial proliferation, resulting in the secretion of excessive fluid. This fluid accumulation compresses surrounding nerves, also leading to joint pain.

4. Bone Hyperplasia

In OA, inflammatory factors induce congestion and edema in surrounding soft tissues, fostering the development of aseptic inflammation. Prolonged exposure to these factors triggers bone hyperplasia, which compresses nearby nerves, causing joint pain.

Moreover, conditions like rheumatoid arthritis and ankylosing spondylitis may also present similar symptoms. It is imperative for patients to promptly seek medical attention and adhere to prescribed treatments.