What are the Effects of Leuprolide Microsphere Injection?
The main function of Leuprolide Microsphere Injection is to suppress sex hormones. Clinically, it is mainly used to treat endometriosis, uterine fibroids, and other conditions. It can also help improve symptoms such as lumbar pain, menstrual hypermenorrhea, and can be used to treat prostate cancer, central precocious puberty, and other diseases. However, it should not be used by lactating or pregnant women as it may cause bone damage.
1. In the early stages of medication, due to the stimulation of the drug on the gonadal axis, there may be a slight increase in bone pain or varying degrees of urinary retention and spinal cord compression symptoms. Appropriate symptomatic treatment is sufficient. However, for elderly patients or those with previous renal dysfunction, spinal cord compression symptoms or urinary retention may worsen during medication, so caution is advised.
2. When using this drug for treatment, it is essential to distinguish it from similar diseases such as malignancies. If there is no significant improvement in tumor enlargement, medication should be discontinued promptly. This drug can cause a decrease in estrogen levels in the body, leading to osteoporosis and bone loss. Osteoporosis often manifests as bone pain and joint pain.
3. Long-term use of this drug may have certain side effects, which may cause liver damage, elevated transaminase or lactate dehydrogenase levels, and gastrointestinal irritation, resulting in symptoms such as anorexia, nausea, and vomiting. It may also cause increased vaginal discharge, breast tenderness and atrophy, and irregular vaginal bleeding in female patients.
