Is there a kidney transplant option for those with uremia?

Uremia can be treated through kidney transplant surgery, but this surgery is generally less performed. Uremia is not an independent disease, but a clinical syndrome shared by advanced kidney diseases, and it is the final stage of chronic renal failure. The main causes of uremia are renal failure caused by chronic kidney diseases, such as primary glomerulonephritis, diabetic nephropathy, hypertensive kidney damage, hereditary kidney diseases, drugs and poisons, etc. In addition, chronic infections, urinary tract obstruction, hypertension, diabetes, etc., can also cause uremia.

1. Primary glomerulonephritis: If the patient has primary glomerulonephritis, and the lesion is relatively minor, manifesting only as a small amount of proteinuria or no proteinuria, with no significant renal function damage, kidney transplant surgery can be considered;

2. Diabetic nephropathy: If the blood sugar control of diabetic patients is poor, it may lead to diabetic nephropathy, which gradually develops into uremia. At this time, insulin therapy is generally recommended to reduce the damage of blood sugar to the kidneys. If the patient's urine volume is above 500ml/min and creatinine exceeds 707μmol/L, renal replacement therapy can be considered, such as hemodialysis and peritoneal dialysis;

3. Hypertensive kidney damage: If some hypertensive patients cannot control their blood pressure well and hypertension persists, it may lead to chronic renal failure and cause uremia. At this time, alternative treatment options such as peritoneal dialysis need to be used under the guidance of a doctor;

4. Hereditary kidney diseases: Such as polycystic kidney disease, hereditary nephritis, thin basement membrane nephropathy, etc. These diseases are generally caused by congenital factors and usually cannot be treated with kidney transplant;

5. Drugs and poisons: If the patient has a history of exposure to drugs and poisons and develops acute renal failure after taking medication or exposure to poisons, which then develops into uremia, hemodialysis treatment is generally required under the guidance of a doctor.

In addition to the above reasons, if the patient has urinary system obstruction or urinary system injury caused by trauma or other reasons, and is not treated in time, it may develop into uremia.