What does a Complete Quantitative Comparison Chart for Hepatitis B Look Like?

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Quantitative Comparison Table for Hepatitis B: Its Significance and Interpretation

The quantitative comparison table for hepatitis B serves as a reliable medical data source. Through conducting a hepatitis B two-half and five-item test, various indicators are extracted and their numerical values are compared against the values in the quantitative comparison table for hepatitis B. This comparison can be used to determine the presence of hepatitis B virus infection. Typically, the quantitative comparison table for hepatitis B is standardized across hospitals, and it mainly includes hepatitis B surface antigen, E antibody, and other markers.

1. Clinical Significance of Hepatitis B Two-Half and Five-Item Tests

The hepatitis B two-half (five-item) test is currently the most commonly used serological marker for detecting hepatitis B virus (HBV) infection in domestic hospitals. It reflects three pairs of immunological markers for hepatitis B virus, with the core antigen typically not tested, hence the colloquial term "two-half." This test is a preliminary screening tool to determine whether a person is infected with hepatitis B or to roughly estimate the level of viral replication. The results of the hepatitis B five-item test only indicate the presence of hepatitis B virus markers and can determine whether the body has been infected with hepatitis B virus or has antibodies. It can distinguish whether a person is infected with hepatitis B virus, but it cannot confirm whether the person is a hepatitis B patient, a hepatitis B virus carrier, or has other diseases associated with hepatitis B virus, such as post-hepatitis B cirrhosis or hepatocellular carcinoma.

2. Interpretation of Hepatitis B Markers

(1) HbsAg (Surface Antigen): A positive result indicates the presence of hepatitis B virus infection, which may be acute or chronic, or the individual may be a carrier of the hepatitis B virus.

(2) HbeAg (e Antigen): A positive result indicates hepatitis B virus infection with high infectivity and active disease progression.

(3) Anti-HBc: A positive result indicates hepatitis B virus infection.

(4) Anti-HBcIgM: A positive result indicates a recent infection.

(5) Anti-HBcIgG: A positive result indicates a past infection.

(6) Anti-HBe: A positive result indicates hepatitis B virus infection with low infectivity and relatively stable disease condition. Anti-HBs: A positive result suggests a previous hepatitis B virus infection or vaccination against hepatitis B, and the presence of antibodies indicates a protective immune response.