What Medications Are Effective for Long-Standing Gastric Ulcers?

Update Date: Source: Network

Patients with long-standing gastric ulcers can follow their doctor's instructions to take acid-suppressing medications, medications that protect the gastric mucosa, and medications to eradicate Helicobacter pylori infections for treatment. It is recommended that such individuals promptly seek medical attention and select appropriate medications under the guidance of a physician.

I. Acid-Suppressing Medications

1. Proton Pump Inhibitors (PPIs): Examples include Omeprazole Enteric-Coated Capsules and Pantoprazole Sodium Enteric-Coated Tablets, which inhibit the secretion of gastric acid by gastric parietal cells, reducing the irritation caused by gastric acid on the gastric mucosa.

2. H2 Receptor Blockers: Such as Ranitidine Hydrochloride Capsules and Famotidine Tablets. These drugs compete with histamine for H2 receptors, thereby inhibiting gastric acid secretion.

II. Medications to Protect the Gastric Mucosa

Commonly used medications include Colloidal Bismuth Subcitrate Capsules and Bismuth Potassium Citrate Granules. By forming a thin film in the stomach, they isolate the stomach from the aggression of food and gastric juice, thereby alleviating symptoms.

III. Medications to Eradicate Helicobacter Pylori Infections

In cases of long-standing Helicobacter pylori infections, a quadruple therapy regimen is necessary to eliminate the bacteria, consisting of two antibiotics plus a bismuth preparation plus a PPI. The antibiotics can include Amoxicillin Capsules and Clarithromycin Tablets, while the bismuth preparation is either Bismuth Potassium Citrate Granules or Colloidal Bismuth Subcitrate Capsules. PPIs typically chosen are Omeprazole Enteric-Coated Capsules and Lansoprazole Enteric-Coated Tablets. Additionally, traditional Chinese medicines like Kangfuxin Liquid and Xiangsha Yangwei Pills can be used to improve uncomfortable symptoms.

In daily life, it is important to maintain regular eating habits, avoid overeating, quit smoking and alcohol, and reduce the intake of spicy and irritating foods to prevent exacerbating the condition.