Can Colchicine Be Used to Treat Gout?

Gout can be treated with colchicine. Colchicine is the preferred classic drug for the acute attack of gout, which can relieve joint pain and inflammation within a few hours of taking the drug. However, colchicine is only a painkiller used during acute gout attacks. If you want to completely treat gout, you also need to take uric acid-lowering drugs during the intermittent period of gout attacks. Commonly used uric acid-lowering drugs include febuxostat, allopurinol, and benzbromarone. Only by using these uric acid-lowering drugs during the intermittent period of attacks and controlling the blood uric acid level below 360μmol/L can the acute attacks of gout be prevented and reduced. The effect of colchicine in the treatment of gout is still relatively good, especially in the early stage of acute attacks.

If the patient's treatment is ineffective, it may be related to delayed treatment time, and the time of administration is a bit late. Colchicine is mainly used to treat gout during acute attacks to relieve the symptoms of joint swelling and pain. During the intermittent period of attacks, colchicine is generally not used for treatment. Regarding the therapeutic dose of colchicine, large doses of colchicine were used in the past. Firstly, take 2 tablets orally at a time, and then take 1 tablet every hour until nausea, vomiting and other gastrointestinal reactions occur, and then stop. The general daily dose does not exceed 6mg. Due to excessive toxic and side effects, it is currently advocated to use low-dose colchicine to treat gout, which is 1 tablet at a time, 3 times a day.