"What Causes Gout?"
Gout: Causes, Symptoms, and Treatment
Gout is a disease caused by the deposition of uric acid crystals in joints due to excessively high levels of blood uric acid. Its etiology encompasses congenital purine metabolism disorders, medication effects, and improper diet.
Etiology
- Congenital Purine Metabolism Disorders: If a patient has a congenital disorder in purine metabolism, it can lead to abnormal purine metabolism in the body, resulting in hyperuricemia.
- Medication Effects: Prolonged use of medications such as diuretics or anti-tuberculosis drugs may reduce uric acid excretion from the body, thereby triggering gout.
- Improper Diet: Regular consumption of high-purine foods like animal livers and seafood can elevate purine levels in the body, increasing the risk of gout.
Treatment
For patients experiencing acute gout attacks, non-steroidal anti-inflammatory drugs (NSAIDs) such as Ibuprofen Sustained-Release Capsules and Diclofenac Sodium Sustained-Release Tablets can be prescribed for pain relief under medical supervision. Additionally, glucocorticoids like Dexamethasone and Methylprednisolone can be administered concurrently as per doctor's advice.
In daily life, patients are advised to maintain healthy habits, avoiding excessive fatigue and staying away from late-night activities to prevent exacerbation of the condition. Furthermore, a balanced diet is crucial, including fresh fruits and vegetables while limiting high-purine foods like pig liver and anchovies.
