What are the Effects and Benefits of Omeprazole Sodium Injection?

There are various types of gastrointestinal diseases, and medications are typically required for treatment. Oral medications may not be effective for some diseases. For instance, oral omeprazole sodium may not effectively treat duodenal ulcer, gastric ulcer, and reflux esophagitis. In such cases, injectable omeprazole sodium may be prescribed. Let's explore the role and benefits of omeprazole sodium injection.

Omeprazole sodium injection inhibits gastric acid production, protecting the gastric mucosa and preventing mucosal damage. This relieves symptoms such as heartburn, acid reflux, and abdominal pain. It is primarily used to treat patients with peptic ulcer or ulcer bleeding, promoting ulcer healing and hemostasis. It can also be used in patients with reflux esophagitis, gastroesophageal reflux disease, or increased gastric acid production to relieve symptoms like heartburn and chest pain. It can also be prescribed for patients with functional dyspepsia, heartburn, and acid reflux. In emergency situations such as acute myocardial infarction, post-major surgery, and post-trauma, it can be used to prevent stress ulcer bleeding. It can also alleviate abdominal pain caused by Zollinger-Ellison syndrome by suppressing gastric acid production.

1. Due to its strong and long-lasting effect on suppressing gastric acid secretion, it is not advisable to use other antacids or acid suppressants simultaneously with this medication. To prevent excessive acid suppression, long-term high-dose use is not recommended for general peptic ulcer diseases (except for patients with Zollinger-Ellison syndrome).

2. This medication can significantly increase the pH value in the stomach, which may affect the absorption of many drugs.

3. No dosage adjustment is required for patients with renal impairment; however, caution is advised for patients with liver impairment, and the dosage may need to be adjusted accordingly.

4. When treating gastric ulcer, gastric cancer should be excluded before using this medication to avoid delayed diagnosis and treatment.

5. For patients taking proton pump inhibitors for a long time, it is essential to be aware of the potential risk of fractures (especially in elderly patients) and regularly monitor blood magnesium levels to prevent hypomagnesemia.

6. Since there is an interaction between proton pump inhibitors and clopidogrel, patients taking clopidogrel are advised to discuss medication safety with their doctors before starting treatment to ensure safe medication use.