What Are the Benefits, Contraindications, and Usage Instructions for Misoprostol Tablets?

Misoprostol tablets have the effects of softening the cervix, enhancing uterine tension, and increasing intrauterine pressure. They can also be used sequentially with mifepristone to significantly increase or induce the frequency and amplitude of spontaneous uterine contractions. They can be used to terminate intrauterine pregnancy within 16 weeks, postpartum hemorrhage, and incomplete abortion. They can also be used to treat duodenal ulcer, gastric ulcer, and other conditions.

1. Misoprostol tablets can also be used for patients with arthritis taking non-steroidal anti-inflammatory drugs (NSAID) who develop duodenal ulcer or gastric ulcer, ensuring that they can continue NSAID treatment.

2. In the absence of oxytocin, misoprostol tablets can also be used as a first-line drug for the treatment of uterine inertia postpartum hemorrhage. The recommended dosage is 200-600 micrograms taken in a single dose or sublingually.

3. The primary mechanism of misoprostol is to reduce gastric acid secretion by inhibiting basal, stimulated, and nocturnal acid secretion, protecting the gastric mucosa, and promoting the healing or relief of peptic ulcers. It is generally suitable for the treatment of duodenal ulcer and gastric ulcer, but contraindicated for pregnant women or women who cannot exclude pregnancy, or women planning pregnancy within one month.

4. When taking misoprostol for medical abortion, it should be done on an empty stomach. Do not eat for two hours after taking the medication, and it must be taken under the guidance of a doctor. It is contraindicated for patients with heart, liver, or kidney diseases, and those allergic to prostaglandins.