What are the causes of developing uremia?
1. Primary or secondary kidney diseases: such as chronic glomerulonephritis, diabetic nephropathy, hypertensive arteriolosclerosis of the glomerulus, thin basement membrane nephropathy, etc., are prone to cause uremia, especially when secondary factors are not resolved, uremia is prone to occur;
2. Chronic kidney diseases (primary or secondary): such as chronic nephritis, nephrotic syndrome, diabetic nephropathy, hypertensive arteriolosclerosis of the glomerulus, etc., have irreversible chronic damage. For example, patients with poorly controlled diabetes may gradually experience declining renal function and gradually develop into uremia;
3. Hereditary kidney diseases: such as polycystic kidney disease, hereditary nephritis, etc., are related to genes, and there is currently no effective treatment;
4. Drug and poison poisoning: patients need to take medication for a long time due to the treatment of diseases, or due to pesticide poisoning, food poisoning, etc., causing body damage, which may induce uremia.
In addition to the relatively common reasons mentioned above, there are other possible diseases, such as chronic urinary tract obstruction, bilateral renal artery stenosis, etc. Moreover, the treatment of patients with uremia should focus on actively treating the primary disease, maintaining water-electrolyte balance, correcting acid-base balance disorders and nutritional metabolic disorders. Medications such as sodium bicarbonate, sodium lactate, furosemide, and calcitriol can be used under the guidance of a doctor to correct metabolic acidosis and actively undergo hemodialysis, peritoneal dialysis, etc., to prolong the patient's life.
