Does blood pressure tend to be low in cases of uremia?
Uremia is a syndrome composed of a series of clinical manifestations that occur when chronic renal failure enters the terminal stage. The reasons for hypotension in patients with uremia may include low volume, excessive cardiac load, and insufficient effective circulating blood volume.
1. Low volume: Whether it is hemodialysis or peritoneal dialysis, patients with uremia will lose a certain amount of water. Excessive water loss will lead to a decrease in effective circulating blood volume and cause vasoconstriction of peripheral blood vessels. At this time, the low effective circulating blood volume will lead to hypotension.
2. Excessive cardiac load: Patients with uremia often have hypertension, which can increase the cardiac load. If combined with coronary heart disease, myocardial infarction, etc., it will be more likely to lead to cardiac insufficiency. Cardiac insufficiency can also lead to a low effective circulating blood volume, resulting in hypotension.
3. Insufficient effective circulating blood volume: Patients with uremia, whether hemodialysis or peritoneal dialysis, will have a certain amount of proteinuria. Proteinuria can cause a low effective circulating blood volume. In addition, there will be a large amount of dehydration after dialysis, and the insufficient blood volume caused by dehydration is the main reason for hypotension. In addition, patients with uremia often have anemia, which is a common complication of chronic renal failure patients. Since the kidney is the main organ for producing erythropoietin, reduced erythropoietin secretion after kidney injury will lead to anemia. If anemia is not corrected, it may lead to low systolic blood pressure in patients.
In addition, long-term chronic kidney disease can also lead to anorexia, malnutrition, and decreased immunity, which can also cause hypotension.
