Why Do Small Blisters Appear on Hands During Spring?

Hand Blisters in Spring: Common Causes and Treatments

In spring, the appearance of small blisters on the hands is typically associated with conditions such as dyshidrotic eczema and peeling palmoplantar keratoderma. Details are as follows:

1. Dyshidrotic Eczema

Also known as pompholyx, the exact cause and pathogenesis of dyshidrotic eczema remain unclear, though it may be related to excessive sweating or impaired sweat evacuation. It commonly occurs in spring and autumn. Most patients develop deep-seated blisters on the palmar and flexor surfaces of their fingers bilaterally. After the fluid dries, peeling may occur, often without significant itching. Early treatment focuses on drying the skin, with topical application of calamine lotion. Once peeling occurs, topical corticosteroid creams such as triamcinolone acetonide ointment, desonide ointment, or fluticasone propionate cream can be applied. If topical medications are ineffective, short-term oral corticosteroids like prednisone, triamcinolone, or methylprednisolone may be prescribed.

2. Peeling Palmoplantar Keratoderma

Affecting both palms, peeling palmoplantar keratoderma initially presents as pinpoint-sized blisters without itching or other subjective symptoms. It is more common in adults and typically occurs at the end of spring and beginning of summer, resolving spontaneously in autumn. No specific treatment is usually required, but low-concentration keratolytics and gentle lubricants like urea ointment, oxidative ointment, or medical Vaseline can be applied externally if necessary.