How Should Hydrochloric Acid Metoclopramide Injection Be Administered?

Update Date: 2024-06-06 Source: Network

Metoclopramide Hydrochloride Injection

Metoclopramide Hydrochloride Injection is mainly used to treat vomiting. It is administered mainly through intramuscular or intravenous injection. The specific dosage should be determined by the doctor based on the patient's age, condition, and other factors. Do not use it blindly without consultation.

I. Metoclopramide Hydrochloride Injection

Metoclopramide Hydrochloride Injection is an antiemetic drug.

1. It is used for vomiting caused by chemotherapy, radiotherapy, surgery, craniocerebral injury, sequelae of brain trauma, sea and air operations, and drug-induced vomiting;

2. It is used for the symptomatic treatment of nausea and vomiting symptoms caused by various diseases such as acute gastroenteritis, biliary pancreatitis, uremia, etc.;

3. It is used before diagnostic duodenal intubation to facilitate smooth intubation; during gastrointestinal barium X-ray examination, it can reduce nausea and vomiting reactions and promote the passage of barium.

II. Dosage and Administration

Intramuscular or intravenous injection. For adults, 10-20mg (1-2 ampoules) per time, with a daily dose not exceeding 0.5mg/kg; for children under 6 years old, 0.1mg/kg per time, and for children aged 6-14 years, 2.5-5mg (0.25-0.5 ampoules) per time. The dose should be halved for patients with renal insufficiency.

III. Precautions

Metoclopramide Hydrochloride Injection is ineffective for vomiting caused by motion sickness; aldosterone and serum prolactin concentrations may increase due to the use of metoclopramide; the dose for patients with severe renal insufficiency should be reduced by at least 60%, and these patients are prone to extrapyramidal symptoms; intravenous injection of metoclopramide should be slow, completed in 1-2 minutes, rapid administration may cause agitation and restlessness, followed by a state of lethargy. Since this drug can reduce the oral bioavailability of cimetidine, if both drugs must be used together, the interval should be at least 1 hour; the toxicity of this drug increases when it turns yellow or yellowish brown upon exposure to light.