What Are the Clinical Applications of Metronidazole?

Metronidazole is clinically used to treat trichomoniasis, periodontitis, and gingivitis, as well as to improve symptoms such as gingival bleeding. After using metronidazole, there may be gastrointestinal and nervous system reactions, as well as skin allergies such as urticaria, rash, and dermatitis, or leukopenia. Therefore, once such reactions occur, they must be taken seriously.

1. It was initially used to treat trichomoniasis and later widely applied to the treatment of anaerobic infections.

2. It has good therapeutic effects on periodontitis and necrotic ulcerative gingivitis.

3. It can also improve gingival bleeding, periodontal abscess, and control acute symptoms of HIV-related periodontitis.

4. Metronidazole can effectively kill obligate anaerobes without causing imbalance of flora.

1. Oral administration may cause adverse reactions such as anorexia, nausea, vomiting, diarrhea, constipation, and abdominal spasms.

2. Nervous system reactions may include depression, headache, mental confusion, and peripheral neuropathy.

3. Other side effects may include prolonged vaginal candidiasis, colitis, allergies, and urticaria.

4. A few patients may experience cystitis, difficulty urinating, numbness, and abnormal sensations in their limbs.

5. Seizures are the most severe nervous system side effect, especially when high doses are used or treatment is prolonged.

6. Transient and mild leukopenia, rash, and dermatitis may also occur.