Why does Tacrolimus Ointment Cause Skin to Appear More Pale with Continued Use?

The increasingly white skin caused by Tacrolimus Ointment is mostly due to drug side effects, skin immune metabolic dysfunction, and decreased melanocytes. It is necessary to go to the hospital for examination to determine the cause, and effective ways to improve should be chosen according to the cause. Strict compliance with the doctor's advice is required during the use of the drug. If adverse conditions are found, it is necessary to stop using it. Here are the possible reasons:

Before using this medication, it is necessary to consult a doctor. Long-term use may have side effects on the skin, some of which may be accompanied by whitening. If the condition is not severe, it will improve after stopping the medication.

Long-term use of this medication may have a certain impact on the immune system metabolism, which may also be accompanied by increasingly white skin. It is best to stop using it or switch to another medication.

During the use of the medication, the melanocytes in the body may gradually decrease. When the melanin becomes less and less, it can cause local skin whitening, affecting the appearance, and the use of the medication should be stopped.