"Are there any complications associated with gout?"
Gout is a metabolic disorder characterized by the deposition of uric acid crystals in joints due to excessively high levels of serum uric acid. Its complications encompass renal lesions and joint deformities.
1. Acute Kidney Injury: Chronic interstitial nephritis and urinary tract stones can arise from long-term hyperuricemia, leading to acute kidney failure.
2. Hypertension: There is a close relationship between hypertension and hyperuricemia, with approximately 30% to 40% of patients suffering from hypertension, often accompanied by obesity, diabetes, dyslipidemia, and impaired glucose tolerance.
3. Tophi: Also known as gouty nodules or uric acid crystals, tophi are small, white, yellow, or pink nodules that commonly appear on the auricle, metatarsophalangeal joints, interphalangeal joints, metacarpophalangeal joints, wrists, elbows, and ankles, with a symmetrical distribution. When tophi erode bone tissue, they can cause fractures and disabilities.
4. Renal Lesions: These include urinary tract obstruction, hydronephrosis, renal insufficiency, and in severe cases, may progress to kidney failure.
Repeated gout attacks can lead to joint deformities, such as finger curvature and collapsed arches, impacting daily life and work. It is recommended to maintain a light diet and avoid high-purine foods to prevent exacerbation of the condition. In case of discomfort, prompt medical attention is essential.