What Are the Potential Risks of Elevated Cholinesterase Levels?

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Cholinesterase and Its Significance in Medical Examinations

Cholinesterase is a commonly used biomarker in medical tests, particularly for patients with liver diseases. Elevated cholinesterase levels often indicate poor prognosis and active disease states, suggestive of significant decline in enzyme activity. In such cases, prompt and active treatment is warranted. In this article, we will briefly explore the potential harms associated with elevated cholinesterase levels and discuss relevant nutritional considerations.

I. Potential Harms of Elevated Cholinesterase Levels

1. Acute Viral Hepatitis: The decrease in serum cholinesterase levels in patients is related to the severity of the disease, which may not necessarily correlate with the degree of jaundice. Persistent decrease in enzyme activity often suggests poor prognosis.

2. Chronic Hepatitis: In patients with chronic persistent hepatitis, the activity of this enzyme remains relatively stable. However, in patients with chronic active hepatitis, the enzyme activity is similar to that seen in acute hepatitis.

3. Liver Cirrhosis: During the compensatory stage, serum cholinesterase levels are often normal. However, in the decompensatory stage, the enzyme activity decreases significantly.

II. Nutritional Considerations for Elevated Cholinesterase

1. Fresh Vegetables and Fruits: Rich in various vitamins, they can increase the level of vitamin C, promote the activation of the immune system, and enhance the ability of white blood cells to phagocytose bacteria. To a certain extent, they can improve the individual's resistance and strengthen the immune system.

2. Fungi-based Foods: Such as shiitake mushrooms, common mushrooms, black fungus, Hericium erinaceus, and straw mushrooms, these foods can enhance immune function to varying degrees. They promote the increase of white blood cells and mononuclear macrophages, enhance phagocytic function, and facilitate antibody production. These foods activate the immune system and improve immune function, playing a positive role in enzyme reduction.

3. High-Protein Foods: Fish, soy products, and dairy products are rich in protein and are easily digested and absorbed, enhancing the body's ability to fight infections.

III. Causes of Elevated Cholinesterase

Experts explain that cholinesterase is an important indicator in liver function tests as it reflects liver damage. Generally, elevated cholinesterase levels indicate liver injury. Clinically, the main causes of elevated cholinesterase include:

First, various liver diseases such as hepatitis A, hepatitis B, fatty liver, and alcoholic liver disease can cause liver damage. Once the liver is damaged, hepatocyte degeneration or necrosis can lead to elevated cholinesterase levels, making it an important indicator in liver function tests.

Second, besides liver diseases, diabetes, hypertension, thyroid hyperfunction, renal failure, and neurological diseases can also cause elevated cholinesterase levels.

Third, long-term malnutrition, anemia, and organophosphorus poisoning can also lead to abnormal cholinesterase levels.