What Should I Know About Bisoprolol Tablets?

Bisoprolol tablets are a type of Western medicine in the form of small white pills, primarily used for hypertensive patients. However, due to the numerous contraindications and precautions associated with its use, it is essential to follow the doctor's instructions when taking this medication, and it should not be discontinued without proper medical advice.

Bisoprolol tablets are indicated for the treatment of hypertension and coronary heart disease (angina pectoris). They are also prescribed for patients with moderate to severe chronic stable heart failure accompanied by decreased ventricular contractile function (ejection fraction ≤ 35%, determined by echocardiography).

Prior to using this medication, it is necessary to comply with the doctor's instructions and undergo treatment with ACE inhibitors, diuretics, and, optionally, cardiac glycosides. Additionally, bisoprolol may pose a risk to pregnant women or fetuses/newborns.

Generally, β-adrenergic receptor antagonists can reduce placental perfusion, which is associated with growth retardation, intrauterine death, resorption, and preterm birth. In fetuses and newborns, adverse reactions such as hypoglycemia and bradycardia may occur. If the use of a β-adrenergic receptor antagonist is necessary, a selective β1-adrenergic receptor antagonist is preferred.

Unless specifically indicated, bisoprolol should not be used by pregnant women. If its use is deemed necessary, close monitoring of uterine-placental blood flow and fetal growth is recommended. If harmful effects on the mother or fetus are observed, alternative treatment options should be considered.

Newborns should be closely monitored as hypoglycemia and bradycardia are most likely to occur within the first three days of life. It is unclear whether this medication is excreted in human milk, therefore, its use is not recommended for breastfeeding women.

Common adverse reactions associated with bisoprolol include neurological abnormalities such as dizziness and headache, as well as bradycardia.