What Are the Benefits of Taking Gikarbestartan Tablets?

Nowadays, more and more hypertensive patients need to control their blood pressure changes through antihypertensive drugs. However, for different symptoms and patients, the antihypertensive drugs used are also different. Jiajia Ebesartan Tablets belong to the ARB class of antihypertensive drugs, which can be taken for a long time by hypertensive patients, and the antihypertensive effect is also relatively ideal. If adverse reactions occur when using Jiajia Ebesartan Tablets, the drug can also be changed. The indication of Jiajia Ebesartan Tablets is hypertension. The main ingredient of this product is irbesartan, and its usage and dosage are as follows: Oral administration: the recommended initial dose is 0.15g (1 tablet), once a day. Depending on the condition, it can be increased to 0.3g (2 tablets), once a day. It can be used alone or combined with other antihypertensive drugs. For severe hypertension and unsatisfactory blood pressure reduction after drug increment, small doses of diuretics (such as thiazides) or other antihypertensive drugs can be added. After oral administration, this product can be rapidly absorbed with a bioavailability of 60% to 80%, which is not affected by food. The peak plasma time is 1 to 1.5 hours, and the elimination half-life is 11 to 15 hours. Steady state is reached within three days. Irbesartan is metabolized by glucuronidation or oxidation, and in vitro studies have shown that it is mainly oxidized by cytochrome P4502C9. This product and its metabolites are excreted through the biliary tract and kidneys. The plasma protein binding rate of irbesartan is 90%. According to domestic data, after healthy subjects took 300mg of this product orally, the peak blood concentration was reached at about 1.9 hours, with a peak concentration of about 4058μg/L, and the elimination half-life (t1/2β) was about 10.2 hours. Common adverse reactions include headache, dizziness, palpitations, etc. Occasional cough is usually mild and transient, and most patients can tolerate continued medication. Rare cases of urticaria and angioneurotic edema have occurred. As an antihypertensive drug, Jiajia Ebesartan can be taken for a long time to control blood pressure. In addition to drug treatment, it is also recommended that patients drink more water, eat a low-salt and low-fat diet, adhere to physical exercise, and avoid staying up late and overexertion for a long time, which can help accelerate the improvement of the condition.