"How Does Gout Attack Occur?"

Update Date: Source: Network

Causes of Gout Attacks

Gout attacks can stem from various factors, commonly non-disease-related such as improper diet, medication effects, and infectious factors. They may also be associated with genetic predisposition, renal dysfunction, and uric acid excretion disorders. Below are the primary categories:

Non-Disease Factors

  1. Improper Diet: Frequent consumption of high-purine foods like animal viscera or seafood can elevate uric acid levels in the body, triggering gout.
  2. Medication Effects: Certain medications like Furosemide and Azathioprine can affect the body's uric acid metabolism, leading to gout.
  3. Infectious Factors: Bacterial or viral infections may alter blood urea levels, potentially increasing the risk of gout.

Disease Factors

  1. Genetic Factors: Having a family history of gout significantly increases one's risk of developing the condition.
  2. Renal Dysfunction: Renal insufficiency often impedes uric acid excretion, causing uric acid levels in the blood to rise, thereby inducing gout.
  3. Uric Acid Excretion Disorders: Conditions like congenital enzyme deficiencies can hinder normal uric acid excretion, leading to uric acid crystal formation in joints and subsequent gout attacks.

Additionally, prolonged exposure to cold environments, heavy alcohol consumption, and underlying conditions like diabetes and hypertension can also contribute to gout attacks. It is recommended to maintain a balanced diet and engage in regular exercise to help prevent disease progression.