Is Tiotropium Bromide Administered for a Treatment Duration of 4 Years?
The main component of Tiotropium Bromide Spray is tiotropium bromide. This product is a bronchodilator suitable for the treatment of chronic obstructive pulmonary disease, including chronic bronchitis and emphysema. It can treat accompanying dyspnea, prevent acute exacerbation, and improve the quality of life of COPD patients, reducing the frequency of acute exacerbations of COPD. Is the treatment period for Tiotropium Bromide four years? Let's take a look.
Firstly, regarding the question of whether the treatment period for Tiotropium Bromide is four years, it is not recommended to use this drug for a long time as it can lead to drug resistance. All drugs are a double-edged sword, and it is not true that the more drugs, the better. Excessive use can harm physical and mental health. This drug is long-acting, and the general recommended dosage is one capsule inhaled through an inhalation device once daily, without exceeding the recommended dose. The half-life is generally five to six days after inhalation, with 14% of the dose excreted and the remainder excreted through feces. Renal elimination is greater than creatinine elimination, indicating that the drug is secreted into the urine. For patients with chronic obstructive pulmonary disease, continuous inhalation for two to three weeks can achieve pharmacokinetic steady state, and further drug accumulation is not required afterwards.
These are the relevant introductions to the above drugs. However, long-term use may have certain adverse reactions, including dry mouth, dry throat, increased heart rate, glaucoma, difficulty urinating, urinary retention, constipation, etc. These symptoms will improve after discontinuation of the drug.
Secondly, Tiotropium Bromide Spray (Spiriva® Respimat®) mainly contains tiotropium bromide as a bronchodilator. It is suitable for the maintenance treatment of chronic obstructive pulmonary disease (COPD), including chronic bronchitis and emphysema, as well as the maintenance treatment of accompanying dyspnea and prevention of acute exacerbation. It can improve the quality of life of COPD patients and reduce acute exacerbations of COPD. There is also a tiotropium bromide powder inhaler available as an alternative.
Thirdly, regarding the dosage and administration, this product is only for inhalation use. The bottle containing tiotropium bromide can only be inserted into the Respimat inhalation device and inhaled through it (see instructions for use). One medicinal dose contains two actuations. The recommended dosage for adults is one inhalation through the Respimat inhalation device at the same time every day, with two actuations each time (see instructions for use). The recommended dose should not be exceeded.
