Uremia is a syndrome consisting of a series of clinical manifestations that occur after chronic kidney disease enters the terminal stage. The early symptoms of uremia are not typical. As the disease progresses, symptoms such as increased urine output, skin itching, anemia, nausea, vomiting, abdominal distension, diarrhea, palpitations, chest tightness, etc. may gradually appear. Here are the detailed symptoms:
1. Increased Urine Output: Patients with uremia may experience increased urine output in the early stages, often manifesting as increased nocturia, especially during quiet sleep at night.
2. Skin Itching: The decreased inactivation of estrogen in the skin of patients with uremia can lead to dry and itchy skin. Additionally, secondary skin conditions like dermatitis and eczema are common in uremia patients, which can also cause skin itching.
3. Anemia: As the kidneys are vital metabolic organs, kidney disease can impede the excretion of metabolic waste, resulting in the accumulation of toxins in the body and causing anemia.
4. Nausea and Vomiting: Some patients may experience decreased appetite, nausea, and vomiting in the early stages, which can lead to gastrointestinal bleeding in severe cases.
5. Abdominal Distension and Diarrhea: Due to the impaired metabolic function of the intestine in uremia patients, it is difficult to digest high-protein foods, leading to symptoms like abdominal distension and diarrhea.
6. Palpitations and Chest Tightness: In the early stages of uremia, water and sodium retention can cause palpitations and chest tightness.
7. Other Symptoms: Patients may also experience fatigue, dizziness, insomnia, irritability, and other neurological symptoms. When toxins affect the heart system, it can cause chest tightness and shortness of breath.
Due to significant individual differences, early symptoms of uremia may vary, and some patients may not experience any specific symptoms. If patients experience unexplained urine abnormalities or other uncomfortable symptoms, it is recommended to actively seek medical attention.
