Is leukemia caused by a lack of platelets?

Differences Between Thrombocytopenia and Leukemia

Thrombocytopenia typically refers to a decrease in platelet count, whereas leukemia does not involve a reduction in platelets. These two conditions are distinct diseases. Thrombocytopenia can be primary, while leukemia is a malignant clonal disorder of bone marrow hematopoietic stem cells.

1. Primary Thrombocytopenia

This primarily involves a decrease in platelet count without other significant symptoms. It may manifest as skin bleeding, increased menstrual flow in women, nosebleeds, or gum bleeding. Some patients may experience intracranial bleeding, numbness or pain in limbs.

2. Secondary Thrombocytopenia

This can be caused by other diseases such as aplastic anemia, myelodysplastic syndromes, or autoimmune diseases, and is not necessarily attributed solely to low platelet counts. Clinical presentations vary widely, including skin petechiae, ecchymoses, increased menstrual flow in women, or even extensive bleeding.

Understanding Leukemia

Leukemia is a malignant clonal disorder that originates from bone marrow hematopoietic stem cells. Leukemia cells proliferate excessively within the bone marrow and release pyrogenic substances, causing fever. Leukemia progresses rapidly, and prompt treatment is crucial upon diagnosis to prevent severe anemia, bleeding, and even life-threatening complications.

If leukemia is suspected, blood tests and other necessary examinations such as bone marrow aspiration should be performed. Upon confirmation, treatment with medications like Azacitidine Injection and Dexamethasone Sodium Phosphate Injection under medical guidance is recommended. Additionally, chemotherapy and radiotherapy are viable treatment options.