What Does a Low Complement C1q Level Indicate?
Complement C1q can activate the human immune response, and a low level of complement C1q indicates that the activation of the human immune response has been hindered and limited. The cause of the disease is not yet clear, and patients may experience varying degrees of symptoms. Therefore, when complement C1q is low, it is important to undergo timely and effective testing, determine the cause of the disease, and then carry out targeted treatment to control the progression of the disease.
Low complement C1q is often seen in active mixed connective tissue disease. Early patients with low complement C1q typically experience symptoms such as fatigue, weakness, joint pain, finger swelling or sclerosis, pulmonary inflammatory changes, myalgia, muscle weakness, esophageal dysfunction, lymph node enlargement, hair loss, skin rash, etc. Currently, the specific cause of low complement C1q is not yet clear.
Low complement C1q can also present with overlapping characteristics in clinical manifestations, and the manifestations of different patients vary widely. In the absence of typical clinical manifestations, patients can exercise a certain degree of control over unexplained fever. During the examination of complement C1q, patients should avoid eating overly greasy food. Additionally, the alcohol content in the blood will directly affect the test results. For patients with a history of blood clots, special arrangements should be made and informed in advance.
The treatment for low complement C1q typically focuses on symptomatic treatment and controlling the progression of the disease. The treatment plan and dosage should follow individualized principles and observe drug side effects in real-time. Targeted drugs can be used to treat low complement C1q within a certain time frame. Glucocorticoids have good therapeutic effects on arthritis, skin rash, serositis, myositis, anemia, leukopenia, and vasculitis caused by low complement C1q.
Patients with erosive arthritis without kidney damage caused by low complement C1q can be treated with rheumatoid arthritis treatment protocols.
