"How long does it typically take for jaundice-induced yellowing of the whites of the eyes to subside?"

Physiological and Pathological Jaundice in Newborns

Typically, when newborns develop physiological jaundice, their skin and sclera turn yellow within 2-3 days after birth. Pathological jaundice, on the other hand, requires assessment based on the underlying cause.

1. Physiological Jaundice

If the jaundice gradually subsides by the 4th to 5th day after birth, and the baby is in good spirits, it is considered a normal physiological phenomenon requiring no specific treatment.

2. Breast Milk Jaundice

For babies exclusively fed with breast milk, jaundice may occur within 7-10 days of birth and persist or worsen. In such cases, breastfeeding should be suspended to observe for improvement. If symptoms do not significantly improve, probiotics may be prescribed by a doctor to regulate intestinal function, while breastfeeding can continue. After discontinuation, liver function and bilirubin levels should be reassessed. If indicators are normal, breastfeeding can be resumed. Most cases resolve spontaneously within about 6 weeks, while a few may persist up to 9 months or longer.

3. Hemolytic Disorders

These are commonly seen in ABO and Rh incompatibility-induced neonatal hemolytic disease, particularly in infants born to RH-negative mothers. This condition can lead to ocular fundus yellowing accompanied by anemia, edema, and in severe cases, may threaten life. Timely medical attention is advised for diagnostic tests, and if necessary, phototherapy can be used to reduce unbound bilirubin levels and alleviate jaundice. Alternatively, exchange transfusion can remove sensitized antibodies from the blood to achieve cure. Premature infants are more prone to jaundice due to their weaker liver metabolic capacity. Parents should closely monitor their infants' mental status and feeding, and promptly seek medical attention upon detecting any abnormalities.